---What’s the matter your sister?-She has a cold.A. with; badB. on; badC. with; badlyD

问题补充：

---What’s the matter your sister?

---She has a cold.

A. with; bad

B. on; bad

C. with; badly

D. on; badly

答案：

(答案→)A. with; bad

B. on; bad

C. with; badly

D. on; badly

解析：句意：你的妹妹怎么了？她患了重感冒。What’s the matter with sb?……怎么了？用介词with，have a bad cold患重感冒，故选A。