“Tommy run！Be quick！The house is on fire！”the mother shouted with clearly in her voice.A.

问题补充：

“Tommy，run！Be quick！The house is on fire！”the mother shouted，with clearly in her voice.

A. anger

B. rudeness

C. regret

D. panic

答案：

A. anger

B. rudeness

C. regret

(答案→)D. panic

解析：句意：“汤米，快跑！快点儿！房子失火了！”妈妈叫喊着，声音里明显带着恐慌。anger生气；rudeness粗鲁；regret懊悔，遗憾；panic恐慌。D项符合语意。