—OK I've had enough of it.I give up.—You can't your responsibilities.A. run off withB. ru

问题补充：

—OK，Ive had enough of it.I give up.

—You can your responsibilities.

A. run off with

B. run up against

C. run out of

D. run away from

答案：

A. run off with

B. run up against

C. run out of

(答案→)D. run away from

解析：考查动词短语辨析。句意：——好了，我已经受够了，我放弃。——你不能逃避你的责任。run away from意为“逃离，逃避”，符合语境。