99Tcm-DTPA,~(99)Tc~m-DTPA
clearance of 99m TcDTPA99Tcm-DTPA清除率
3)~(99)Tc~(m)99Tcm
1.A new imaging agent for β-amyloid plaques,~(99)Tc~(m)-MAMA-DMABP was prepared,and its biodistribution in normal mice was studied.制备了新的Aβ斑块显像剂99Tcm-酰胺基氨基二硫醇(MAMA)-4-氨基-4′-二甲氨基联苯(DMABP),并研究了其在正常小鼠体内的生物分布。
2.In order to investigate in vivo absorption and distribution of gelatin after injection intravenously,gelatin was directly labeled with reduced ~(99)Tc~(m) that was formed by reduction of ~(99)Tc~(m)O~-_(4) with NaBH_(4).为考察明胶静脉注射后在机体内的吸收及分布情况,用99Tcm对明胶进行整体标记,然后将标记物99Tcm-明胶静脉注射于小鼠和家兔体内,检测不同时间后标记物的生物分布。
4)~(99)Tc~m99Tcm
1.Ciprofloxacin(CPF) made in China is labeled with ~(99)Tc~m and the factors which affects the labeling efficiency are determined.确定了99Tcm-环丙沙星(ciprofloxacin,CPF)的最佳标记条件,在此基础上制备了环丙沙星冻干品药盒,并初步观察了99Tcm-CPF在炎症模型小鼠体内的分布。
2.~(99)Tc~m-HYNIC-Annexin Ⅴ has been successfully evaluated in animal models and the results show that the cell apoptosis can be assaied by which.结果表明:每个AnnexinⅤ的蛋白分子能偶连2个HYNIC,标记率为98%,标记物的放化纯度在6 h后仍然>95%;99Tcm-HYNIC-AnnexinⅤ在动物模型中能有效检测细胞凋亡。
3.The complexes ~(99)Tc~mN-DMCHI and ~(99)Tc~m-DMCHI are prepared by ligand exchange reaction and directly labeling method,respectively.分别通过配体交换法和直接标记法制备得到放化纯大于95%的脂溶性配合物99TcmN DMCHI和99Tcm DMCHI,二者在室温下均可稳定6h以上。
5)99 Tc m99Tcm
1.AIM: To explore the method of99 Tc m direct labeling of angiostatin (AS) and to investigate the stability and biological activity of99 Tc m AS in vitro .目的 :探索用99Tcm 直接标记血管抑素 (angiostatin ,AS)的方法 ,并研究标记产物的体外稳定性及其生物活性 。
2.Based on the labeling c myc mRNA oligonucleotide with99 Tc m, the labeling compounds are entrapped with liposome.在 99Tcm 标记 DNA的基础上 ,采用阳离子脂质体对其进行包裹 ,获得了脂质体介导的 99Tcm-DNA。
3.Objective To label monoclonal antibodies (McAb) with99 Tc m via 2-IT.目的研究 2 -IT法99Tcm 间接标记单克隆抗体。
6)99Tc m99Tcm
1.The new compound is labeled by99Tc m and the labeling yield is 84.合成了γ 硫脲基丙基锗倍半硫化物 ,进行了99Tcm的标记 ,在配体量为 0 5mg,SnCl2 量为 0 。
延伸阅读
technetium 99Tcm di-ethylenetriaminepentaacetic acid(DTPA)injection分子式：CAS号：性质：在无菌条件下，高锝99m酸钠注射液与含亚锡的DTPA注射液反应得到的无色澄明无菌溶液，是放射性诊断用药。99Tcm-DTPA可用作肾功能显像剂测定肾小球滤过率和脑显像剂。
